Mito Plus: India’s breakthrough in indigenous 3D bioprinting

December 3, 2025 Incredible India Valli Sarvani

Indian tech start-up Avay Biosciences has created Mito Plus, a new bio-3D printer made in India. It can print human tissues.

This is an important achievement for India’s growing bioprinting field.

The first prototype has already been set up at the Indian Institute of Science (IISc) in Bengaluru.

This shows that the start-up is ready to provide advanced bioprinting tools to major research centres.

Mito Plus was launched at the Bengaluru Tech Summit in 2022. It is an improved version of Avay’s earlier bio-3D printer.

The upgrades were made using scientific input from Dr. Bikramjit Basu’s research group at IISc.

Co-founded by Suhridh Sundaram, an IIT Madras alumnus, Avay Biosciences is among the few Indian start-ups developing both hardware and software fully in-house, offering end-to-end bioprinting capabilities within the country.

The innovation behind Mito Plus lies in its precision engineering and versatile biomaterial printing capabilities.

According to CEO Manish Amin, the printer can handle a wide range of biomaterials and includes UV curing, a HEPA filtration system, and advanced temperature-control features that allow the printhead and printbed to operate between 4°C and 80°C.

This flexibility is crucial for maintaining cell viability and printing complex tissue structures required in drug discovery, cancer biology, cosmetology and regenerative research.

Amin explained that 3D bioprinting functions much like conventional 3D printing but replaces plastics or metals with biomaterials containing living cells, which are layered to form tissues such as skin or liver.

Although full organ printing is still years away, he emphasised that bioprinting is already transforming research by offering reliable, ethically viable and physiologically relevant human tissue models.

Avay’s innovation is even more significant because 70% of the manufacturing is done in Chennai and Bengaluru, supported by an in-house software team that is continuously improving the technology.

This localised production lowers costs and enables wider access to advanced bioprinting tools in India.

COO Suhridh Sundaram said the company is working with ICT Mumbai to create bioprinted skin for burn patients.

They are also developing skin for toxicology testing. This work is an important step toward creating organs in the future.

As the global bioprinting market is expected to grow quickly, innovations like Mito Plus help India become a strong competitor in advanced biomedical engineering.

Image Credit: Avay tech Website Screenshot