Stratus variant XFG: Fast spread, low risk so far

July 14, 2025 Hot from the Oven Valli Sarvani

The World Health Organization (WHO) is tracking a new COVID-19 variant called XFG, also known as Stratus.

This variant is a recombinant strain, meaning it formed when a person was infected with two different COVID-19 variants, LF.7 and LP.8.1.2, at the same time.

Recombinant variants always begin with “X” in their name. XFG is a descendant of the Omicron family and was first detected in Canada.

The earliest known sample was collected on January 27. Since then, 1,648 genome sequences have been reported across 38 countries, according to the global GISAID database.

It carries multiple mutations in the spike protein, which helps the virus infect human cells.

Because of these changes, XFG spreads quickly and evades parts of the immune system. Still, WHO currently classifies the global risk as low.

So far, symptoms linked to XFG remain mild. Like other Omicron subvariants, it mostly affects the upper respiratory system.

Some countries, especially in Southeast Asia, are seeing a rise in hospital admissions. However, severe illness is not increasing in the same way.

The Lancet warns that XFG has a high immune escape ability. This could make it harder for the body to fight off infection.

Even so, vaccines in use are expected to remain effective. They still help prevent serious symptoms and reduce hospitalisations.

WHO has added XFG to its “Variants Under Monitoring” list. That means health experts are observing it for changes in severity or spread.

Tracking helps detect potential threats early and plan quick responses. Experts advise people to continue basic precautions.

Masks, hand hygiene, and vaccine boosters remain key tools. These small steps can help avoid pressure on health systems.

In India and elsewhere, alertness can reduce risk without causing panic. Preventing a surge is always cheaper in both terms, i.e. in money and lives, than reacting too late.

Image by Tmaximumge from Pxhere (Free for commercial use / CC0 Public Domain)

Image Published on April 17, 2020